Associate Scientist Job at Pacer Group, South San Francisco, CA

ZFdXZGU4RFVjV1ZBWjBNNGRzTUtmdnpaRXc9PQ==
  • Pacer Group
  • South San Francisco, CA

Job Description

Job Title: Scientist - II

Duration: 12 Months

Location: South San Francisco, CA 94080

Summary:

Education and experience required:

  • B.S. degree in Biochemistry, Cell/Molecular Biology, Bioprocess engineering or related fields and three (3) years of industry or academia experience or a M.S. degree with 1 year of experience in similar fields

Must haves:

  • Prior experience in mammalian cell culture techniques, and cell culture media preparation is a prerequisite: single use mammalian cell culture tools employed in bioprocess development, including but not limited to deep well plates and shake flasks.
  • Perform transient and stable transfections for protein expression in mammalian cells (CHO, HEK293).
  • Ability to multi-task different protocols at once, handle concurrent projects simultaneously with high attention to detail.

Nice to haves/preferred:

  • Experience with high-throughput systems and automation.
  • Experience with batch purification using a variety of scaffolds and basic QC.
  • Industry experience is preferred.

Software skills:

  • Basic knowledge on biological data collection and analysis tools (Vicell, metabolite analyzers) and computer applications such as ELN, MS Word, MS Excel and MS PowerPoint.
  • Experience with data and reagent management software such as Dotmatics, Benchling, Spotfire, etc is preferred.

Skills/techniques needed:

  • Excellent aseptic techniques and familiarity with principles of sterilization/disinfection.
  • Strong communication, organizational, and interpersonal skills.
  • Able to maintain a “can-do” attitude and act with a sense of urgency to complete innovative projects while being flexible in work priorities based on business needs.
  • Understand and adhere to corporate standards regarding code of conduct, safety, appropriate handling of materials
  • Able to troubleshoot cell culture system and think critically about experiments.
  • Must be comfortable with physical activities of constant standing, walking, and sitting with arm stretching into biosafety cabinets for cell culture work.

Responsibilities:

Department summary:

  • Our teams combine leading drug discovery capabilities and world-class R&D with the purpose of turning breakthrough science into life-changing medicines.
  • We are looking for a motivated scientist to be an integral part of the Protein Science department within Discovery Biologics at Client’s Research Labs- South San Francisco.
  • The successful candidate will be involved in multiple aspects of the production of recombinant proteins, monoclonal antibodies, multispecific scaffolds, and novel protein modalities to enable all aspects of Early Discovery.
  • Ideally, the candidate will be able to execute and develop on techniques involving recombinant protein expression in CHO cells using both transient and stable-pool techniques.
  • Additionally, the candidate should have foundational experience in purification and QC, along with a proven ability to accurately record and present data.

Job responsibilities in detail:

  • Maintain and propagate CHO cells in suspension culture independently to support ongoing projects in a cell culture lab.
  • Perform transient and stable transfections for protein expression in mammalian cells (CHO, HEK293). Express and batch purify a variety of proteins (monoclonal, bispecific antibodies, VHHs, Fabs, Fc-Fusions, etc.) using both resin and magnetic-bead immunoprecipitation methods.
  • Execute fed-batch experiments in a variety of platforms: shake flasks 125ml to 5L, tube spins and multi-well plates.
  • Perform analytical measurements for cell growth, metabolite measurements and HPLC analysis of titers from supernatant.
  • Analyze purified proteins using techniques: SDS-PAGE, HPLC, UPLC, CESDS, Nano-drop, UV-Vis.
  • Maintain and troubleshoot mammalian cell culture systems.
  • Document protein production processes, prepare reports and communicate results
  • ELN documentation.

Key skills:

  • Maintain and propagate CHO cells in suspension culture independently
  • Perform transient and stable transfections for protein expression in mammalian cells(CHO cells).
  • Purification batch purification using bench top.
  • Candidate should have foundational experience in purification and QC

Job Tags

Flexible hours,

Similar Jobs

CoMark

Entry Level Marketing Job at CoMark

 ...Entry Level Marketing As a part of our Entry Level Marketing team, you will be responsible for providing retail sales, marketing, and customer service experience that is intended to improve the profitability of our clients and retail partners. CoMark is a marketing... 

Carney, Sandoe & Associates

Digital Art Teacher Job at Carney, Sandoe & Associates

 ...Carney, Sandoe & Associates, an education recruitment firm, is currently seeking a Digital Art Teacher fo r for the 2025-2026 school year at an independent school in the Fairfax, VA area. About CS&A: Our free job placement service connects educators with independent... 

VitalCore Health Strategies

Dentist Job at VitalCore Health Strategies

 ...DDS) SCHEDULE ~ Part-Time DENTIST (DMD, DDS) POSITION SUMMARY As the Dentist, you will utilize your expertise in dental surgery, restorative dentistry, oral surgery, and general dental care to provide high-quality dental services to our patients in a correctional... 

TeamSoft

Int. (5-7+yrs) Workplace Service Desk Analyst w/ Cisco UCM, PunchDown, & vendor management expertise Job at TeamSoft

Intermediate (5-7+yrs) Workplace Service Desk Analyst Location: Cincinnati, OH Duration: Contract to hire. Contract for at least 3 months possibly more prior to becoming an FTE. Onsite 5 days a week until they truly get up to speed. After they can potentially...

Icahn School of Medicine at Mount Sinai

Medical Assistant II-Selikoff Centers for Occupational Health-Suffern Job at Icahn School of Medicine at Mount Sinai

 ...Required Issuing Authority: AHA Employer Description Strength through Unity and Inclusion The Mount Sinai Health System is committed to fostering an environment where everyone can contribute to excellence. We share a common dedication to...